Publicaciones

DAWRIN PECH-PUCHA, MAR PEREZ-POVEDANO, MARTA MARTINEZ-GUITIAN, CRISTINA LASARTE-MONTERRUBIO, JUAN CARLOS VÁZQUEZ-UCHA, GERMÁN BOU, JAIME RODRÍGUEZ, ALEJANDRO BECEIRO, AND CARLOS JIMÉNEZ
In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa
Marine Drugs  2020, 18, 336
doi:10.3390/md18060326

DAWRIN PECH-PUCH, MAR PEREZ-POVEDANO, MARTA MARTINEZ-GUITIAN, CRISTINA LASARTE-MONTERRUBIO, JUAN CARLOS VÁZQUEZ-UCHA, MARÍA LOURDES NOVOA-OLMEDO, GERMÁN BOU, JAIME RODRÍGUEZ, ALEJANDRO BECEIRO, AND CARLOS JIMÉNEZ
Marine organisms from the Yucatan Peninsula (Mexico) as a potential natural source of new antibacterial compounds"
Marine Drugs  2020,18, 369
doi:10.3390/md18070369

DAWRIN PECH-PUCH, JUDITH BERASTEGUI-CABRERA, MAR PEREZ-POVEDANO, HAROLD VILLEGAS-HERNANDEZ, SERGIO GUILLÉN-HERNÁNDEZ, BASTIEN CAUTAIN, FERNANDO REYES, JERÓNIMO PACHÓN, PATRICIA GÓMEZ, JAIME RODRÍGUEZ, CARLOS JIMÉNEZ, AND JAVIER SÁNCHEZ-CÉSPEDES
Antiviral and antiproliferative potential of marine organisms from the Yucatan Peninsula, Mexico
Frontiers in Marine Science, section Marine Biotechnology  2020, 7, 607
doi: 10.3389/fmars.2020.00607

Marine Natural Products from the Yucatan Peninsula
Dawrin Pech-Puch, Mar Pérez-Povedano, Oscar A. Lenis-Rojas Jaime Rodríguez and Carlos Jiménez
Marine Drugs 2020, 18, 59
doi:10.3390/md18010059

Cytotoxic furanoditerpenes isolated from the sponge Spongia tubulifera collected in the Mexican Caribbean
Dawrin Pech-Puch, Jaime Rodríguez, Carlos Alfredo Sandoval-Segura and Carlos Jiménez
Marine Drugs 2019, 17, 416
DOI: 10.3390/md17070416

Anti-inflammatory effects of 5α,8α-epidioxycholest-6-en-3β-ol, a steroidal endoperoxide isolated from Aplysia depilans through bioguided fractionation and NMR Anaylisis
Renato B. Pereira, David M. Pereira, Carlos Jiménez, Jaime Rodríguez, Rosa M. Nieto, Romeu Videira, Olga Silva, Paula B. Andrade and Patrícia Valentão
Marine Drugs 2019, 17, 330
DOI: 10.3390/md17060330

Combining JCBA and Marfey’s Methodology to Determine the Absolute Configuration of Threonines: The case of Gunungamide A, a New Cyclic Depsipeptide Containing Chloropyrrole from the Sponge Discodermia sp.
Guillermo Tarazona, Rogelio Fernandez, Patricia Cruz, Marta Pérez, Jaime Rodriguez, Carlos Jiménez and Carmen Cuevas
Organic Chemistry Frontiers. 2019, 6, 15-21,
DOI: 10.1039/c8qo00961a

Marine natural Products in medicinal chemistry
Carlos Jiménez
ACS Medicinal Chemistry Letters 2018, 10, 959-961
DOI: 10.1021/acsmedchemlett.8b00368

AHL-lactonase expression in three marine emerging pathogenic Vibrio spp. reduces virulence and mortality in brine shrimp (Artemia salina) and Manila clam (Venerupis philippinarum)
Marta Torres, José Carlos Reina, Juan Carlos Fuentes-Monteverde, Gerardo Fernández, Jaime Rodríguez, Carlos Jiménez and Inmaculada Llamas
PlosOne 2018, 13, e0195176
doi.org/10.1371/journal.pone.0195176

Njaoamine I, a cytotoxic polycyclic alkaloid from the Haplosclerida sponge Haliclona (Reniera) sp.
Carlos Urda, Marta Pérez, Rogelio Fernández, Jaime Rodríguez, Carlos Jiménez and Carmen Cuevas
Tetrahedron Letters 2018, 59, 2577-2580                                              
doi.org/10.1016/j.tetlet.2018.05.059

Peruvioses A to F, sucrose esters from the exudate of Physalis peruviana fruit as α-amylase inhibitors
Carlos-A. Bernal, Leonardo Castellanos, Diana M. Aragón, Diana Martinez-Matamoros, Carlos Jiménez, Yolima Baena and Freddy A. Ramos
Carbohydrate Research, 2018, 461, 4-10.
DOI.org/10.1016/j.carres.2018.03.003

Can Stereoclusters Separated by two Methylene Groups Be Related by DFT Studies? The case of the Cytotoxic Meroditerpenes Halioxepines
Guillermo Tarazona, Gonzalo Benedit, Rogelio Fernandez, Marta Perez, Jaime Rodriguez, Carlos Jiménez and Carmen Cuevas
Journal of Natural Products, 2018, 81, 343-348
DOI: 10.1021/acs.jnatprod.7b00807

Daedophamide, a Cytotoxic Cyclodepsipeptide from the Sponge Daedalopelta sp collected in Indonesia
Carlos Urda, Rogelio Fernandez, Jaime Rodriguez, Marta Pérez, Carlos Jiménez and Carmen Cuevas
Journal of Natural Products, 2017, 80, 3054-3059
DOI: 10.1021/acs.jnatprod.7b00678

Bistratamides M and N, oxazole-thiazole containing cyclic hexapeptides isolated from Lissoclinum bistratum. Interaction of zinc (II) with bistratamide K 
Carlos Urda, Rogelio Fernandez, Jaime Rodriguez, Marta Pérez, Carlos Jiménez and Carmen Cuevas
Marine Drugs, 2017, 15, 209.
DOI: 10.3390/md15070209

Cytotoxic Anomoian B and Aplyzanzine B, New Bromotyrosine Alkaloids from Indonesian Sponges
Guillermo Tarazona, Gema Santamaría, Patricia G. Cruz, Rogelio Fernández, Marta Pérez, Juan Fernando Martínez-Leal, Jaime Rodriguez, Carlos Jiménez and Carmen Cuevas
ACS Omega 2017, 2, 3494-3501.
DOI: 10.1021/acsomega.7b00417

Protoxenicins A and B, cytotoxic long chain acylated xenicanes from the soft coral Protodendron repens Carlos Urda, Rogelio Fernandez, Marta Pérez, Jaime Rodriguez, Carlos Jiménez and Carmen Cuevas Journal of Natural Products, 2017, 80, 713-719.
DOI: 10.1021/acs.jnatprod.7b00046

Cereusitin A: A Cyclic tetrapeptide from a Bacillus cereus strain isolated from the soft coral Antillogorgia (syn. Pseudopterogorgia) elisabethae ANGELA PINZÓN-ESPINOSA, DIANA MARTINEZ-MATAMOROS, LEONARDO CASTELLANOS, CARMENZA DUQUE, JAIME RODRIGUEZ, CARLOS JIMÉNEZ Y FREDDY ALEJANDRO RAMOS Tetrahedron Letters , 58-634- 637, 2017
DOI: 10.1016/j.tetlet.2017.01.002

Pembamide, a N-Methylated Linear Peptide from a sponge Cribrochalina sp Carlos Urda, Marta Pérez, Jaime Rodriguez, Carlos Jiménez, Carmen Cuevas y Rogelio Fernandez Tetrahedron Letters 57, 3239-3242, 2016
doi.org/10.1016/j.tetlet.2016.05.054

Lanesoic Acid: An Cytotoxic Zwitterion from Theonella sp Jaime Rodriguez, Carlos Jiménez, Maria Blanco, Guillermo Tarazona, Rogelio Fernandez y Carmen Cuevas Organic Letters 18, 5832-5835, 2016
DOI: 10.1021/acs.orglett.6b02832

Cytotoxic and Antimicrobial Diterpenes Isolated from Hyptis dilatata. Fausto Alvarez, Edisson Tello, Katherine Bauer, Luis E. Diaz, Jaime Rodriguez and Carlos Jimenez. Current Bioactive Compounds, 11, 189-197, 2015

3-Nitroasterric acid derivatives from the Antarctic sponge-derived fungus Pseudogymnoascus sp .
Luis Figueroa, Carlos Jiménez, Jaime Rodríguez, Carlos Areche, Renato Chávez, Marlene Henríquez, Mercedes De La Cruz, Caridad Díaz, Yuri Segade, Inmaculada Vaca
Journal of Natural Products 78, 919-:923, 2015

Mass Spectrometry Detection of Minor New Meridianins from the Antarctic Colonial Ascidian Aplidium falklandicum (A. meridianum) 
Laura Núñez-Pons, Rosa Maria Nieto, Conxita Avila, Carlos Jimenez , Jaime Rodríguez
Journal of Mass Spectrometry 50, 103-111, 2015

Photodamage attenuation effect by a tetraprenyltoluquinol chromane meroterpenoid isolated from Sargassum muticum
E.M. Balboa, Y.-X. Lic, B.-N. Ahnc, S.-H. Eomc, H. Domínguez, Carlos Jimenez, Jaime Rodríguez
Journal of Photochemistry and Photobiology B: Biology, 148, 51-58, 2015

Thelepamide: An Unprecedented Ketide-Amino Acid from Thelepus crispus, a Marine Worm 
Jaime Rodríguez, Rosa M. Nieto, María Blanco, Frederick A. Valeriote, Carlos Jiménez, Phillip Crews
Organic Letters, 2014, 16, 464-467

El papel de los productos naturales en el mercado farmacéutico actual
Carlos Jiménez
Anales de Química  2013, 109, 134-141

An approach to speed up the Isolation of Hydrophilic Metabolites from Natural Sources at Semipreparative Level by using a HLB/MCX- HPLC/MS system. 

Alfonso Espada, Cristina Anta, A. Bragado, Jaime Rodríguez, Carlos Jiménez
J. Chromatogr. A 2011, 1218, 1790-11754

New cytotoxic cembranolides: Isolation, biogenetic studies, and synthesis of analogues.
M. Isabel Nieto, Noemí González, Jaime Rodríguez, Russell G. Kerr, Carlos Jiménez.
Tetrahedron 2006, 62, 11747-11754

New Cytotoxic Cembranes from Cnidaria Gyrophyllum sibogae.
Fernando Reyes, Ana Ardá, Rocio Martín, Rogelio Fernández, Ana Rueda, David Montalvo, Cristina Gómez, Carlos Jiménez, Jaime Rodríguez, José Mª Sánchez-Puelles
J. Nat. Prod. 2004, 67, 1190-1192

New Dammarane Triterpenes from the aerial parts of Ibicella lutea grown in Argentina.
Mario J. Simirgiotis, Carlos Jiménez, Jaime Rodríguez, Oscar S. Giordano, Carlos E. Tonn
J. Nat. Prod. 2003, 66, 1586-1592

Triterpene Glycosides From The Far Eastern Sea Cucumber Cucumaria conicospermium
Sergey A. Avilov, Alexander A. Antonov, Vladimir I. Kalinin, Anatoly I. Kalinovsky, Pavel S. Dmitrenok, Valentin A. Stonik, Ricardo Riguera, Carlos Jimenez
J. Nat. Prod. 2003, 66, 910-916

Evaluation of the effects of several zoanthamine-type alkaloids on the aggregation of human platelets.
Rosa M. Villar, José Gil-Longo, Antonio H. Daranas, María L. Souto, José J. Fernández, Solange Peixinho, Miguel A. Barral, Gilmar Santafé, Jaime Rodríguez, Carlos Jiménez
Bioorg. Med. Chem. 2003, 11, 2301-2306

Triterpene Glycosides from the Deep-Water North-Pacific Sea Cucumber Synallactes nozawai Mitsukuri.
Alexandra S. Silchenko, Sergey A. Avilov, Alexandr A. Antonov, Vladimir I. Kalinin, Anatoly I. Kalinovsky, Alexey V. Smirnov, Ricardo Riguera, Carlos Jiménez
J. Nat. Prod. 2002, 65, 1802-1808

Cyclobutenbriarein A, The First Diterpene With A Tricyclo[8.4.0.03,6]Tetradec-4-Ene Ring System Isolated From The Gorgonian Briareum Asbestinum.
Noemi Gonzalez, Jaime Rodriguez, Russell G. Kerr, Carlos Jiménez
J. Org. Chem. 2002, 67, 5117-5123

Novel Cytotoxic Oxygenated C29 Sterols from the Colombian Marine Sponge Polymastia tenax. Gilmar Santafe, Vanessa Paz, Jaime Rodriguez, Carlos Jiménez
J. Nat. Prod. 2002, 65, 1161-1164

A New Secosterol from the Indonesian Octocoral Pachyclavularia violacea.
Cristina Anta, Noemi Gonzalez, Jaime Rodriguez, Carlos Jiménez
J. Nat. Prod. 2002, 65, 1357-1359

New Xenia Diterpenoids from the Indonesian Soft Coral Xenia sp.
Cristina Anta, Gilmar Santafe, Noemi Gonzalez, Jaime Rodriguez, Carlos Jiménez
J. Nat. Prod. 2002, 65, 766-768

New Cytotoxic Steroids from the Gorgonian Isis hippuris. Structure-Activity Studies.
Noemi Gonzalez, Miguel A. Barral, Jaime Rodriguez, Carlos Jiménez.
Tetrahedron 2001, 57, 3487-3497

A New Cytotoxic Alkaloid from the Marine Bacteria Agrobacterium sp. Agrochelin.
Librada M. Cañedo, Jesus Angel De La Fuente, Cristina Gesto, Maria J. Ferreiro, Carlos Jiménez, Ricardo Riguera.
Tetrahedron Let. 1999, 40, 6841-6844

Triterpene Glycosides from the Far-Eastern Sea Cucumber Pentamera calcigera. I. Monosulfated glycosides and cytotoxicity of their unsulfated derivatives
Sergey A. Avilov, Alexandr S. Antonov, Olga A. Drozdova, Vladimir I. Kalinin, Anatoly I. Kalinovsky, Valentin A. Stonik, Ricardo Riguera, Luis A. Lenis, Carlos Jiménez
J. Nat. Prod. 2000, 63, 65-71.

Hemolytic Polar Steroidal Constituents of the Starfish Aphelasterias japonica.
Natalia V. Ivanchina, Alla A. Kicha, Anatoly I. Kalinovsky, Pavel S. Dmitrenok, Valentin A. Stoni*, Ricardo Riguera, Carlos Jiménez
J. Nat. Prod. 2000, 63, 1178-1181.

Triterpene Glycosides from the Far Eastern Sea Cucumber Pentamera calcigera II: DisulfatedGlycosides
Sergey A. Avilov, Alexandr S. Antonov, Olga A. Drozdova, Vladimir I. Kalinin, Anatoly I. Kalinovsky, Ricardo Riguera, Luis A. Lenis, Carlos Jiménez
J. Nat. Prod. 2000, 63, 1349-1335

The Occurrence of the Human Glycoconjugate C2- -D-Mannosylpyranosyl-L-tryptophan in Marine Ascidians
Angel Garcia, Luis A. Lenis, Carlos Jiménez, Cecile Debitus, Emilio Quiñoá, Ricardo Riguera
Org. Lett. 2000, 2, 2765-2767

Absolute Structures of New Briarane Diterpenoids from Junceella fragilis
Miguel Garcia, Jaime Rodriguez, Carlos Jiménez
J. Nat. Prod. 1999, 62, 257-260

Didemniserinolipids A-C, Unprecedented Serinolipids from the Tunicate Didemnum sp. Noemi Gonzalez, Jaime Rodriguez, Carlos Jiménez
J. Org. Chem. 1999, 64, 5705-5707

Frondoside-C, A New Nonholostane Triterpene Glycoside from the Sea Cucumber Cucumaria frondosa: Structure and cytotoxicity of its unsulfated derivative
Sergey A. Avilov, Olga A. Drozdova, Vladimir I. Kalinin, Anatoly I. Kalinovsky, Valentin A. Stonik, Elena N. Gudimova, Ricardo Riguera, Carlos Jiménez
Can. J. Chem. 1998, 76, 137-141

New Briarane Stecholide Diterpenes from the Indonesian Gorgonian Briareum sp.
Jaime Rodriguez, Rosa M. Nieto, Carlos Jiménez
J. Nat. Prod. 1998, 61, 313-317

The Unusual Presence of Hydroxylated Furanosesquiterpenes in the Deep Ocean Tunicate Riterella rette . Chemical Interconvertions and Absolute Sterochemistry
Luis A. Lenis, M. J. Ferreiro, Cecile Debitus, Carlos Jiménez, Emilio Quiñoa, Ricardo Riguera.
Tetrahedron 1998, 54, 5385-5406

Minalemines A-F: Sulfamic Acid Peptide Guanidine Derivatives isolated from the Marine Tunicate Didemnun rodriguesi
M. Angeles Exposito, Blanca López, Rogelio Fernández, M. Jesús Vázquez, Cecile Debitus, Teresa Iglesias, Carlos Jiménez, Emilio Quiñoa, Ricardo Riguera
Tetrahedron 1998, 54, 7539-7550

Isolation and Synthesis of the First Natural 6-Hydroxyimino-3-oxo-4-en Steroid from the Sponge Cynachyrella spp.
Lucia Nuñez, Jaime Rodriguez, Solange Peixinho, Carlos Jimenez.
Tetrahedron Let. 1997, 38, 1833-1836

Koreoside A, a New Nonholostane Triterpene Glycoside from the Sea Cucumber Cucumaria koraiensis
S. A. Avilov, A. I. Kalinovsky, V. I. Kalinin, V. A. Stonik, Ricardo Riguera, Carlos Jimenez.
J. Nat. Prod. 1997, 60, 808-810

Structure of Eximisoside A, a Novel Triterpene Glycoside from the Far-Eastern Sea Cucumber Psolus eximis
V. I. Kalinin, S. A. Avilov, E. Y. Kalinina, O. G. Korolkova, A. I. Kalinovsky, V.A. Stonik, R. Riguera, C. Jimenez
J. Nat. Prod. 1997, 60, 817-819

Cytotoxic Triterpene Glycosides from Far-Eastern Sea Cucumbers belonging to the genus Cucumaria
O. A. Drozdova, S. A. Avilov, V. I. Kalinin, A. I. Kalinovsky, V. A. Stonik, R. Riguera, C. Jimenez
Lieb. Ann. Chem. 1997, 2351-2356

Boussingoside E, a New Triterpenoid Saponin from the Tubers of Boussingaultia baselloides.
Alfonso Espada, Carlos Jimenez, Ricardo Riguera
J. Nat. Prod. 1997, 60, 17-19. (Erratum J. Nat. Prod. 1997, 60, 868)

Anti-Aggregant Effects on Human Platelets of the Crude Aqueous Extract and Polar Fractions of the Microalga Dunaliella tertiolecta
R. M. Villar, M. R. Laguna, D. Martínez, L. Nuñez, C. Jiménez
Phytotherapy Research, 1997, 11, 70-72 

Capítulos de Libros

Carlos Jiménez. ”Esquema general del aislamiento y caracterización de productos naturales bioactivos” en El mar como fuente de moléculas bioactivas, Universidad de León, Secretariado de Publicaciones y Medios Audiovisuales, pp. 143-177, ISBN: 84-7719-796-2, 2002.

Carlos Jiménez. ”Marine sulfur-containing Natural Products” en Studies on Natural Products Chemistry”, Ed. Atta-ur.Rahman, Elsevier, Amsterdam, Vol. 25 Bioactive Natural Products (Part F), pp.811-917. ISBN: 0 08 044001 0, 2001.

Jaime Rodríguez. ”Polycyclic amine alkaloids (3-alkylpiperidine alkaloids)-novel marine bioactive compounds: Structure, synthesis and biochemical aspects” en Studies on Natural Products Chemistry, Ed. Atta-ur.Rahman, Elsevier, Amsterdam, Vol. 25 Bioactive Natural Products (Part E), pp 573-681. ISBN: 978-0-444-50643-6, 1999.